Several case studies from non-standard VOC and SVOC thermal remediation sites are reviewed: modification of existing method EPA TO-17 using thermal desorption tubes and sampling syringes for the sampling and analysis of diesel range organics in process vapor; applying a low volume polyurethane foam (PUF) sampling methodology (EPA TO-10A) coupled with existing method EPA TO-9A for sampling and analysis of dioxins in process vapor; method development for durable large capacity solid adsorbent tube for custom SVOC and pesticide analysis; and method development to demonstrate response and recovery of site specific SVOCs in canisters with existing method EPA TO-15. A review of the existing and potential means of measuring perfluoroalkyl substances (PFAS) in vapor will also be addressed, as this will be a consideration for PFAS remediation sites in the future.